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1.
Asian Pac J Cancer Prev ; 24(12): 4133-4138, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-38156848

RESUMO

PURPOSE/OBJECTIVE: The purpose of this study is to investigate the effect of treatment couch and immobilization devices on surface dose for megavoltage photon beams. MATERIAL/METHODS: Percentage surface dose (PSD) measurement was carried out in Elekta Synergy™ Linear accelerator using PTW Markus® Parallel plate ionization chamber of volume 0.05cm3 with water equivalent RW3 Slab phantom (PTW, Germany). The measurement depth was considered at 0.07mm. The reference PSD was measured at 0° gantry angle with 10×10cm2, 20×20cm2 and 30×30cm2 field sizes and 100cm SSD for 4MV, 6MV and 15MV photon beams. For comparison, PSD measurement was carried out at 180° gantry angle inclusion of treatment couch (TC), All in One positioning system (AIO - PS) and Vac lok Cushions (VLC). RESULTS: Beam angle at 0°, for field sizes 10×10cm2, 20×20cm2 and 30×30cm2, the PSD was observed as 30.9%, 40.5%, 48.7% for 4MV; 23.7%, 33.8%, 42.2% for 6MV; and 17.0%, 29.6%, 38.6% for 15MV respectively. Beam angle at 180° with TC, an increase in PSD by maximum of 65.0% for 4MV, 64.9% for 6MV and 55.9% for 15MV as compared to 0° angle. The PSD increased when beam angle was 180° with TC and AIO - PS were 65.0% for 4MV, 67.4% for 6MV, and 60.9% for 15MV than 0° angle. Similarly, increased PSD for beam angle at 180° with TC and VLC were 66.8% for 4MV, 66.8% for 6MV and 61.3% for 15MV as compared to 0° angle. CONCLUSION: For all three-photon energies, at 180° gantry angle, the PSD increased significantly in case of TC, VLC, and AIO - PS for all the field sizes as compared to gantry angle at 0°. It is necessary to consider TC, AIO - PS and VLC during dose calculation to ensure accuracy of patient treatment delivery.


Assuntos
Fótons , Planejamento da Radioterapia Assistida por Computador , Humanos , Fótons/uso terapêutico , Imagens de Fantasmas , Aceleradores de Partículas , Água , Dosagem Radioterapêutica
2.
Asian Pac J Cancer Prev ; 23(4): 1397-1403, 2022 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-35485702

RESUMO

OBJECTIVE: To study the dosimetric importance of Jaw tracking technique in reducing the doses to organs at risk (OAR) while achieving the optimal dose coverage for the target. METHODS: We retrospectively selected ten Glioblastoma cases and for each patient, two plans were created namely Static Jaw Technique Dynamic Intensity Modulated Radiotherapy plan and Jaw Tracking Technique D-IMRT plan with 6 MV for Varian Truebeam™ STx machine using Eclipse Treatment planning system. Both plans were analyzed and compared based on various dosimetric parameters for Planning Target Volume (PTV) and OARs. The dose agreement between the Portal dose image prediction and the portal dosimetry measurement was also analysed  using gamma analysis criteria of 3%/3mm, 2%/2mm and 1%/1mm of dose distance/distance-to-agreement. RESULTS: The dosimetric parameters evaluated for both plans showed that most of the parameters gave significant P values, where D50% of PTV showed a mean difference (Δ) of 0.45 with significant P value, 0.0104. Similarly mean dose, D2%, D98%, D80% to PTV, Conformity Index and Conformation number showed Δ values of 0.45, 0.51, 0.41, 0.40, 0.02 and 0.01 with their significant P values as 0.0138, 0.0172, 0.0313, 0.0466, 0.0279, 0.0561 respectively. The Δ values and significant P values obtained among OARs are 0.54;0.0224 for brainstem, 0.54;0.0017 for RT optic nerve, 0.52;0.0001 for LT optic nerve, 0.59;0.0040 for optic chiasm and for the healthy tissues it showed the values with their mean dose, V5 and V30 parameters as 0.19;0.0115, 0.59;0.0067 and 0.25;0.0125 respectively. The JTT plans showed better passing results of gamma analysis criteria when compared to SJT plans. CONCLUSION: The findings in the studies emphasize the importance of using JTT technique in the radiotherapy treatment plans as it lowers the risk of acute or late toxicity and secondary radiogenic cancers in patients by reducing the OAR doses and achieves better tumor control.


Assuntos
Glioblastoma , Planejamento da Radioterapia Assistida por Computador , Humanos , Radiometria/métodos , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador/métodos , Estudos Retrospectivos
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